5.5. Biomarkers / Phenotypic Markers

Wild Type Tumor
Transgene Expression H&E
Immunohistochemistry
In- situ Hybridization
Smooth Muscle Actin
Neu
Ki67
H&E
Immunohistochemistry
In Situ Hybridization
Smooth Muscle Actin
Neu
Ki67
Elastin
ErbB2
PyV-mT
Nuclear receptors Estrogen Receptor
Progesterone Receptor
Estrogen Receptor
Progesterone Receptor
Myoepithelium Smooth Muscle Actin
Cytokeratin 14
Smooth Muscle Actin
Cytokeratin 14
Luminal Cell Cytokeratin
Cytokeratin 8
Whey Acidic Protein
In-situ Hybridization
Cytokeratin
Cytokeratin 8
Cytokeratin 18
Whey Acidic Protein
E-cadherin
Basement Membrane Anti-Laminin Anti-Laminin
PAS
Trichrome
Proliferation (S-phase)/Apoptosis Ki67/Tunel assays Ki67/Tunel assays
Stroma   Elastin
Other Vascular markers CD31[PECAM]
SMA
Vascular markers CD31[PECAM]
SMA