Due to the courtesy of the Nature Publishing Group we were able to include
material and images that were previously published in Oncogene Reviews
Vol. 19 (8) February 2000 "Mouse Models for Breast Cancer".
Oncogene Review Issue
Dr. H. Jensen (University of California, Davis) graciously provided us with her slide collection. Dr. Jensenís images illustrate the subgross (three-dimensional) histology and pathology of the human breast. Dr. Jensen also annotated the images.
Dr. Suzana Couto (University of California, Davis) courteously provided slides of cat and dog mammary tumors.
We received additional material from Dr. Carol MacLeod (University of California, San Diego) and Dr. W. Muller (McMaster University, Hamilton, Canada).
Dr. B.H. Min (University of California, Davis) provided the slides for images of human breast cancer.
R. Munn (University of California, Davis) digitized Dr. Jensen's slide collection.
Dr. Ana I. Nieto (Universidad Complutense de Madrid) provided the H&E and whole mount images of the mouse pre-lactating and lactating mammary gland.
Dr. S. Rehm (Smith Kline Beecham Pharmaceuticals) provided us with sample images for the classification of mammary gland proliferative lesions for non-transgenic mice.
Dr. G. Robinson (National Institutes of Health, Bethesda) provided us with the protocol and images of non-radioactive in-situ hybridization. She also gave us editorial support.
Dr. G. Shyamala (Lawerence Berkeley Laboratory) provided the anti-progesterone receptor sera and many of the normal mouse mammary tissues.
J. Walls (University of California, Davis) provided the immunohistochemistry.
Our thanks to Dr. J. Ward (National Institutes of Health, Frederick) for his editorial advice and to Drs. Jose Russo (Fox Chase Cancer Center) and Roy Jensen (Vanderbilt University) for their editorial comments and contributions of images.
The Annapolis meeting was sponsored by the NIH Breast Cancer Think Tank and the NCI Cancer Genome Anatomy Project. The meeting was organized by Drs. Jeffrey Green, Lothar Hennighausen, and Lalage Wakefield (National Institutes of Health, Bethesda).
The Developers of the CD-ROM would like to thank the Annapolis Pathologist Panel: Drs. M. Anver, B. Gusterson, R. Jensen, M. Merino, S. Rehm, J. Russo, F. Tavassoli, J. Ward and R. Cardiff.
We would like to gratefully acknowledge the following Investigators who provided
information, blocks and slides to the slide set:
Drs. R. Callahan, R. Cardiff, R. Coffey, B. Davis, A. Elson, P. Furth, A. Graessmann, C. Graham, J. Green, A. Harrington, L. Hennighausen, S. Jakowlew, R. Jensen, B. Knowles, P. Leder, J. Liang, E. Lukanidin, D. Medina, G. Merlino, H. Moses, W. Muller, I. Nakashima, D. Pravtcheva, G. Radice, J. Rosen, J. Russo, E. Sandgren, E. Schmidt, G. Smith, M. Sternlicht, H. Varmus, and H. Weiher.
Contributions of histology and immunohistochemistry from Dr. Cardiff's laboratory were supported by grants from the State of California, Breast Cancer Research Program (#JB-0014) and from National Institutes of Health (NCRR # U42-RR14905).
This project has been supported in part with Federal funds from the National Institutes of Health (The Cancer Genome Anatomy Project NCI, National Institutes of Diabetes, Digestive and Kidney Diseases and the Center for Information Technology) and under NCI contract no. NO1-CO-56000.
Dr. Cardiff dedicates his contributions to this atlas to Dr. Sefton R. Wellings, his colleague, friend and mentor. Sefton's insights into the comparative biology of the mammary gland were seminal to many of the concepts of mammary preneoplasia that are used today. This atlas reflects his work, insight and dedication.
Ulli Wagner dedicates her contributions to her father, Dr. Siegmar Kleber.